Signal Chain Question

I'm wondering what other people do in this area. When I record bass, for example, I tend to go direct into my interface and then add FX through plug-ins later (unless I am using my Big Muff or Memory Man, even then I may compress or EQ later). Is there an advantage to setting the signal chain first and then recording the bass part (or guitar, vox, drums, etc.)?

With guitar I will mic the amp, use outboard FX, but still may tweak the sound a bit later using plug-ins. So in this instance, again, is there an advantage to setting the sound in advance before recording?

f

Signal Chain Question